We provide tailored protein purification services combining technical expertise with flexible, scalable processes. Supporting early-stage vaccine R&D and broader protein development. We deliver consistent, reliable, high-quality results from research through to large-scale engineering runs.  Full documentation can be provided in the form of Batch Records and CoAs. 

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Protein Production

We can easily scale insect, mammalian and bacterial cells for biomass production up to 40 L or more in shake flasks. Alternatively, we can use our Wave bioreactor system with capacity to 25 L per run, enabling efficient and controlled production at scale. During cell harvest, we utilise high-capacity centrifugation systems or advanced hollow fibre membrane technologies to efficiently recover material from infected cultures prior to purification. 

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Protein Purification

We work closely with you to design the most effective purification strategy, tailored to the target protein sequence, expression system, cell line and key properties such as size, charge, and solubility. Our team uses a broad range of techniques including; affinity chromatography, ion exchange, hydrophobic interaction and size exclusion chromatography, often in combination to maximise purity and yield. We also optimise buffer conditions (pH, salts, and additives such as reducing agents, protease inhibitors and detergents) to maintain protein integrity. Engineering runs can be produced to ‘endotoxin-free’ standards for preclinical applications.

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To view an step by step example of protein purification of eGFP using our pOETeGFP Sf9 reporter plasmid then click here