EXPERTS IN INSECT, MAMMALIAN AND BACTERIAL EXPRESSION

High-Precision Protein Sequencing with Platinum Quantum SI

Oxford Expression Technologies Ltd (OET) is a name you can trust for high-precision protein sequencing services, both here in the UK and globally. Using the advanced Platinum Quantum SI platform, we deliver cutting-edge sequencing with unmatched sensitivity and precision. Whether you are in academic research or industrial development, we are here to support your project from sample submission to final analysis. Find out more below or get in touch with us for more information.

Cutting-edge protein sequencing with the Platinum Quantum SI platform

The Platinum Quantum SI platform delivers high-quality, reproducible protein sequencing results designed to meet the demands of both academic research and industrial applications.

We understand that your samples are often precious or limited. The advanced technology from Quantum SI requires only minimal sample quantities, allowing you to obtain comprehensive sequence data without compromising your valuable materials. Our streamlined workflows ensure rapid turnaround times, allowing you to move your research forward faster.

Our team of proteomics specialists provides thorough data interpretation and insights with every project. We do not simply deliver raw data; we help you understand what the results mean and support you in making informed scientific decisions.

From single proteins to complex biological samples, we provide tailored solutions to fit your unique project needs. Contact our trusted team to discuss your project, request a quotation, or submit your sample and experience the future of protein sequencing.

How can next-generation protein sequencing support your research?

Complete protein identification before committing to downstream experiments

Identify unknown bands from your gels with confidence

Determine which proteins are in a biological samples such as serum

Detect potential contaminants arising from protein purification

Verify that your antibody is successfully isolating the target protein

More info

Case study: identifying an unexpected 8 kDa band as baculovirus P10

In collaboration with Quantum-Si, we used single-molecule protein sequencing to investigate a band of approximately 8 kDa that replaces the expected 10 kDa P10 band on SDS-PAGE gels during the later stages of AcMNPV infection.

The bands were excised, digested with Lys-C and analysed on the Quantum-Si Platinum Pro instrument. The peptide reads confirmed that both bands contained P10, and showed a difference in the C-terminal region of the smaller form.

The results point towards a potential cleavage region downstream of amino acid 72, and further experimental work is needed to establish the precise processing site.

The study shows how protein sequencing can identify the proteins in unexpected gel bands and help investigate differences in protein sequence or processing.

Authors: Jaspreet S. Grewal, Leo P. Graves, Adam Chambers, Linda A. King and Robert D. Possee.

Read the case study